3qcc

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3qcc

Contents 1 Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, orthorhombic crystal form 2 About this Structure 3 See Also 4 Reference

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, orthorhombic crystal form

Template:ABSTRACT PUBMED 21882820

About this Structure

3qcc is a 2 chain structure of Proten tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Proten tyrosine phosphatase

Reference

• Sheriff S, Beno BR, Zhai W, Kostich WA, McDonnell PA, Kish K, Goldfarb V, Gao M, Kiefer SE, Yanchunas J, Huang Y, Shi S, Zhu S, Dzierba C, Bronson J, Macor JE, Appiah KK, Westphal RS, O'Connell J, Gerritz SW. Small molecule receptor protein tyrosine phosphatase gamma (RPTPgamma) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop. J Med Chem. 2011 Oct 13;54(19):6548-62. Epub 2011 Sep 20. PMID:21882820 doi:10.1021/jm2003766

[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]