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1dxa

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Image:1dxa.png

Template:STRUCTURE 1dxa

BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA

Template:ABSTRACT PUBMED 7577946

About this Structure

1dxa is a 2 chain structure. Full experimental information is available from OCA.

Reference

  • Yeh HJ, Sayer JM, Liu X, Altieri AS, Byrd RA, Lakshman MK, Yagi H, Schurter EJ, Gorenstein DG, Jerina DM. NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA. Biochemistry. 1995 Oct 17;34(41):13570-81. PMID:7577946

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