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G09SecL04Tpc2

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Outer Surface Protein A (OspA)

Outer Surface Protein A Fab LA-2 Complex

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Outer surface protein A (OspA) is a major lipoproteinlipoprotein on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with Lyme Diseases uch as late stage neurological disorders.

Introduction to Lyme Disease

Structure

Proteopedia Page Contributors and Editors (what is this?)

Albert Kurian, Nabil Faridi, Michal Harel, Amar Patole

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