4fhj

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Template:STRUCTURE 4fhj

Crystal Structure of PI3K-gamma in Complex with Imidazopyridine 2

Template:ABSTRACT PUBMED 22765895

About this Structure

4fhj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Peterson EA, Boezio AA, Andrews PS, Boezio CM, Bush TL, Cheng AC, Choquette D, Coats JR, Colletti AE, Copeland KW, Dupont M, Graceffa R, Grubinska B, Kim JL, Lewis RT, Liu J, Mullady EL, Potashman MH, Romero K, Shaffer PL, Stanton MK, Stellwagen JC, Teffera Y, Yi S, Cai T, La DS. Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors. Bioorg Med Chem Lett. 2012 Jun 16. PMID:22765895 doi:10.1016/j.bmcl.2012.06.033

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