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Lipases are used by multicellular organisms to break down lipids in the body. They are primarily found in the pancreas, and they operate by dividing triglycerides into diacylglycerols and carboxylates.
Lipases are formed by two tertiary subunits. Each subunit has a calcium ligand, alpha helices, and beta sheets. Histadine is involved in the active site of the enzyme, and lipase has great variety in its specificity. Versene, zinc, copper, mercury, iodine, and PCMB are inhibitors to pancreatic lipase.
