1jx7
From Proteopedia
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Crystal structure of ychN protein from E.coli
Overview
The crystal structure of a conserved hypothetical protein from Escherichia, coli has been determined using X-ray crystallography. The protein belongs, to the Cluster of Orthologous Group COG1553 (National Center for, Biotechnology Information database, NLM, NIH), for which there was no, structural information available until now. Structural homology search, with DALI algorism indicated that this protein has a new fold with no, obvious similarity to those of other proteins with known three-dimensional, structures. The protein quaternary structure consists of a dimer of, trimers, which makes a characteristic cylinder shape. There is a large, closed cavity with approximate dimensions of 16 A x 16 A x 20 A in the, center of the hexameric structure. Six putative active sites are, positioned along the equatorial surface of the hexamer. There are several, highly conserved residues including two possible functional cysteines in, the putative active site. The possible molecular function of the protein, is discussed.
About this Structure
1JX7 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of a conserved hypothetical protein from Escherichia coli., Shin DH, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(1):53-66. PMID:12836674
Page seeded by OCA on Tue Nov 20 18:39:26 2007
