3o5x
From Proteopedia
Contents |
Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor
Template:ABSTRACT PUBMED 20170098
About this Structure
3o5x is a 1 chain structure of Tyrosine phosphatase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3jrl. Full crystallographic information is available from OCA.
See Also
Reference
- Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2010 Feb 19. PMID:20170098 doi:10.1021/jm901645u
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Chan, R J. | Dong, Y. | Gunawan, A M. | He, Y. | Jiang, Z. | Liu, S. | Nabinger, S C. | Wang, L. | Wu, L. | Yang, Z. | Yu, Z. | Zhang, X. | Zhang, Z Y. | Binding affinity | Binding selectivity | Dephosphorylation | Hydrolase | Inhibitor | Receptor | Shp2-iib-08 complex
