1l3z
From Proteopedia
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Crystal Structure Analysis of an RNA Heptamer
Overview
The crystal structure of an alternating RNA heptamer r(GUAUACA) has been, determined to 2.0 A resolution and refined to an R(work) of 17.1% and, R(free) of 18.5% using 2797 reflections. The heptamer crystallized in the, space group C222 with a unit cell of a = 25.74, b = 106.58, c = 30.26 A, and two independent strands in the asymmetric unit. Each heptamer forms a, duplex with its symmetry-related strand and each duplex contains six, Watson-Crick base pairs and 3'-end adenosine overhangs. Therefore, two, kinds of duplex (duplex 1 and duplex 2) are formed. Duplexes 1 stack on, each other forming a pseudo-continuous column, which is typical of the RNA, packing mode, while duplex 2 is typical of A-DNA packing with its termini, in abutting interactions. Overhang adenine residues stack within the, duplexes with C3'-endo sugar pucker and C2'-endo sugar pucker in duplexes, 1 and 2, respectively. A Na+ ion in the crystal lattice is water bridged, to two N1 atoms of symmetry-related A7 bases.
About this Structure
1L3Z is a Protein complex structure of sequences from [1] with NA as ligand. Full crystallographic information is available from OCA.
Reference
The crystal structure of an alternating RNA heptamer r(GUAUACA) forming a six base-paired duplex with 3'-end adenine overhangs., Shi K, Pan B, Sundaralingam M, Nucleic Acids Res. 2003 Mar 1;31(5):1392-7. PMID:12595546
Page seeded by OCA on Sun Nov 25 02:28:09 2007
Categories: Protein complex | Pan, B. | Shi, K. | Sundaralingam, M. | NA | Rna
