2vku
From Proteopedia
Contents |
4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX
Template:ABSTRACT PUBMED 18367444
About this Structure
2vku is a 1 chain structure of Cytochrome P450 with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Eddine AN, von Kries JP, Podust MV, Warrier T, Kaufmann SH, Podust LM. X-ray structure of 4,4'-dihydroxybenzophenone mimicking sterol substrate in the active site of sterol 14alpha-demethylase (CYP51). J Biol Chem. 2008 May 30;283(22):15152-9. Epub 2008 Mar 26. PMID:18367444 doi:10.1074/jbc.M801145200
Categories: Mycobacterium tuberculosis | Sterol 14-demethylase | Eddine, A N. | Kries, J P.Von. | Podust, L M. | Podust, M V. | 4'-dihydroxybenzophenone complex | Alpha-beta | Cyp51-4 | Heme | Heme co-factor | Iron | Lipid synthesis | Metal-binding | Monooxygenase | Nadp | Oxidoreductase | Steroid biosynthesis | Sterol biosynthesis