2c5v

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Template:STRUCTURE 2c5v

Contents 1 DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN 2 About this Structure 3 See Also 4 Reference

DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN

Template:ABSTRACT PUBMED 16492568

About this Structure

2c5v is a 6 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1oku. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2
• Cyclin

Reference

• Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:http://dx.doi.org/10.1016/j.chembiol.2005.11.011