3nee

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Template:STRUCTURE 3nee

Contents

Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)

Template:ABSTRACT PUBMED 20937391

About this Structure

3nee is a 2 chain structure of Transthyretin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Trivella DB, Sairre MI, Foguel D, Lima LM, Polikarpov I. The binding of synthetic triiodo l-thyronine analogs to human transthyretin: Molecular basis of cooperative and non-cooperative ligand recognition. J Struct Biol. 2010 Oct 16. PMID:20937391 doi:10.1016/j.jsb.2010.10.003
  • Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J Struct Biol. 2010 Jun;170(3):522-31. Epub 2010 Mar 6. PMID:20211733 doi:10.1016/j.jsb.2010.03.002

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