1kce

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Image:1kce.png

Template:STRUCTURE 1kce

Contents

E. COLI THYMIDYLATE SYNTHASE MUTANT E58Q IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Template:ABSTRACT PUBMED 8973201

About this Structure

1kce is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Sage CR, Rutenber EE, Stout TJ, Stroud RM. An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q. Biochemistry. 1996 Dec 17;35(50):16270-81. PMID:8973201 doi:http://dx.doi.org/10.1021/bi961269r
  • Stout TJ, Sage CR, Stroud RM. The additivity of substrate fragments in enzyme-ligand binding. Structure. 1998 Jul 15;6(7):839-48. PMID:9687366

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