2vh0
From Proteopedia
Contents |
STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS
Template:ABSTRACT PUBMED 18053714
About this Structure
2vh0 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Convery MA, Diallo H, Hortense E, Irving WR, Kelly HA, King NP, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Zhou P. Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs. Bioorg Med Chem Lett. 2008 Jan 1;18(1):28-33. Epub 2007 Nov 13. PMID:18053714 doi:S0960-894X(07)01328-5
Categories: Coagulation factor Xa | Homo sapiens | Borthwick, A D. | Brown, D. | Burns-Kurtis, C L. | Campbell, M. | Chan, C. | Charbaut, M. | Convery, M A. | Diallo, H. | Hortense, E. | Irving, W R. | Kelly, H A. | King, N P. | Kleanthous, S. | Mason, A M. | Pateman, A J. | Patikis, A. | Pinto, I L. | Pollard, D R. | Senger, S. | Shah, G P. | Toomey, J R. | Watson, N S. | Weston, H E. | Young, R J. | Zhou, P. | Blood coagulation | Cleavage on pair of basic residue | Complex | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Protease | Serine protease | Zymogen
