2boh
From Proteopedia
Contents |
CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH COMPOUND "1"
Template:ABSTRACT PUBMED 15999990
About this Structure
2boh is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Nazare M, Will DW, Matter H, Schreuder H, Ritter K, Urmann M, Essrich M, Bauer A, Wagner M, Czech J, Lorenz M, Laux V, Wehner V. Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography. J Med Chem. 2005 Jul 14;48(14):4511-25. PMID:15999990 doi:http://dx.doi.org/10.1021/jm0490540
Categories: Coagulation factor Xa | Homo sapiens | Bauer, A. | Czech, J. | Essrich, M. | Laux, V. | Matter, H. | Nazare, M. | Ritter, K. | Schreuder, H. | Urmann, M. | Wagner, M. | Wehner, V. | Will, D W. | Blood coagulation factor | Calcium-binding | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydrolase-inhibitor complex | Hydrolase/inhibitor | Hydroxylation | Plasma | Protease | Protein-inhibitor complex | Rational drug design | Serine protease | Serine proteinase | Vitamin k | Zymogen