3b2w
From Proteopedia
Contents |
Crystal structure of pyrimidine amide 11 bound to Lck
Template:ABSTRACT PUBMED 18083554
About this Structure
3b2w is a 1 chain structure of Proto-oncogene tyrosine-protein kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X. N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1172-6. Epub 2007 Dec 5. PMID:18083554 doi:http://dx.doi.org/10.1016/j.bmcl.2007.11.123
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Huang, X. | Atp-binding | Disease mutation | Host-virus interaction | Kinase domain | Lck | Lipoprotein | Membrane | Myristate | Nucleotide-binding | Palmitate | Phosphorylation | Proto-oncogene | Sh2 domain | Sh3 domain | Transferase | Tyrosine-protein kinase
