3s2o
From Proteopedia
Contents |
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure of Beta secretase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Categories: Homo sapiens | Memapsin 2 | Barker, J. | Godemann, R. | Hallett, D. | Kraemer, J. | Madden, J. | Smith, M A. | Alzheimer's disease | Amyloid precursor protein secretase | Aspartic endopeptidase | Aspartic protease | Aspartyl protease | Base | Beta-secretase | Fluorescence polarisation | Fragment-based drug design | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Protease | Transmembrane
