4ajh

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Image:4ajh.png

Template:STRUCTURE 4ajh

Contents

rat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid

Template:ABSTRACT PUBMED 22417091

About this Structure

4ajh is a 4 chain structure of Lactate Dehydrogenase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  • Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Design and synthesis of novel lactate dehydrogenase a inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. Epub 2012 Mar 26. PMID:22417091 doi:10.1021/jm201734r

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