2g8j

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Image:2g8j.png

Template:STRUCTURE 2g8j

Calpain 1 proteolytic core in complex with SNJ-1945, a alpha-ketoamide-type inhibitor.

Template:ABSTRACT PUBMED 16768440

About this Structure

2G8J is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Cuerrier D, Moldoveanu T, Inoue J, Davies PL, Campbell RL. Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography. Biochemistry. 2006 Jun 20;45(24):7446-52. PMID:16768440 doi:10.1021/bi060425j

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