2uxn

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2uxn

Contents 1 STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION 2 About this Structure 3 See Also 4 Reference

STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION

Template:ABSTRACT PUBMED 17529991

About this Structure

2uxn is a 3 chain structure of Lysine-specific histone demethylase 1 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Lysine-specific histone demethylase 1

Reference

• Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H. Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nat Struct Mol Biol. 2007 Jun;14(6):535-9. Epub 2007 May 27. PMID:17529991 doi:http://dx.doi.org/10.1038/nsmb1255
• Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012