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2r9f

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Revision as of 03:52, 17 February 2009 by OCA (Talk | contribs)
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Image:2r9f.png

Template:STRUCTURE 2r9f

Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide

Template:ABSTRACT PUBMED 18702462

About this Structure

2R9F is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Qian J, Cuerrier D, Davies PL, Li Z, Powers JC, Campbell RL. Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions. J Med Chem. 2008 Sep 11;51(17):5264-70. Epub 2008 Aug 15. PMID:18702462 doi:10.1021/jm800045t

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