2vdk

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Image:2vdk.png

Template:STRUCTURE 2vdk

RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE

Template:ABSTRACT PUBMED 18710925

About this Structure

2vdk is a 4 chain structure with sequence from Homo sapiens and Mus musculus. This structure supersedes the now removed PDB entry 1ty3. Full crystallographic information is available from OCA.

Reference

  • Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Aug 25;182(4):791-800. Epub 2008 Aug 18. PMID:18710925 doi:jcb.200801146
  • Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:http://dx.doi.org/10.1038/nature02976

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