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2h5s

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Image:2h5s.png

Template:STRUCTURE 2h5s

Contents

SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase

Template:ABSTRACT PUBMED 17017804

About this Structure

2h5s is a 1 chain structure of Beta-lactamase with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

See Also

Reference

  • Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone. J Am Chem Soc. 2006 Oct 11;128(40):13235-42. PMID:17017804 doi:10.1021/ja063715w

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