2no3

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Image:2no3.png

Template:STRUCTURE 2no3

Contents

Novel 4-anilinopyrimidines as potent JNK1 Inhibitors

Template:ABSTRACT PUBMED 17107797

About this Structure

2no3 is a 4 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Liu M, Wang S, Clampit JE, Gum RJ, Haasch DL, Rondinone CM, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72. Epub 2006 Nov 2. PMID:17107797 doi:http://dx.doi.org/10.1016/j.bmcl.2006.10.093

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