3o23

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Template:STRUCTURE 3o23

Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor

Template:ABSTRACT PUBMED 21441024

About this Structure

3o23 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lesuisse D, Mauger J, Nemecek C, Maignan S, Boiziau J, Harlow G, Hittinger A, Ruf S, Strobel H, Nair A, Ritter K, Malleron JL, Dagallier A, El-Ahmad Y, Guilloteau JP, Guizani H, Bouchard H, Venot C. Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2224-8. Epub 2011 Mar 4. PMID:21441024 doi:10.1016/j.bmcl.2011.03.003

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