1mvg
From Proteopedia
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NMR solution structure of chicken Liver basic Fatty Acid Binding Protein (Lb-FABP)
Overview
Chicken liver basic fatty acid binding protein (Lb-FABP) belongs to the, basic-type fatty acid binding proteins, a novel group of proteins isolated, from liver of different non mammalian species whose structure is not, known. The structure of Lb-FABP has been solved by (1)H NMR. The overall, fold of Lb-FABP, common to the other proteins of the family, consists of, ten antiparallel beta-strands organised in two nearly ortogonal, beta-sheets with two alpha helices closing the protein cavity where small, hydrophobic ligands can be bound. The binding specificity of the protein, is not known, however, based on the high sequence and structural, similarity with an orthologous protein, ileal lipid binding protein, it is, suggested that bile acids may be the putative ligands.
About this Structure
1MVG is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
Solution structure of chicken liver basic fatty acid binding protein., Vasile F, Ragona L, Catalano M, Zetta L, Perduca M, Monaco H, Molinari H, J Biomol NMR. 2003 Feb;25(2):157-60. PMID:12652125
Page seeded by OCA on Tue Nov 20 21:43:49 2007
