3n46

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Image:3n46.png

Template:STRUCTURE 3n46

Contents

Human FPPS complex with NOV_980 and zoledronic acid/MG2+

Template:ABSTRACT PUBMED 20711197

About this Structure

3n46 is a 1 chain structure of Farnesyl diphosphate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Jahnke W, Rondeau JM, Cotesta S, Marzinzik A, Pelle X, Geiser M, Strauss A, Gotte M, Bitsch F, Hemmig R, Henry C, Lehmann S, Glickman JF, Roddy TP, Stout SJ, Green JR. Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat Chem Biol. 2010 Sep;6(9):660-6. Epub 2010 Aug 15. PMID:20711197 doi:10.1038/nchembio.421

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