3ns9

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Template:STRUCTURE 3ns9

Contents 1 Crystal structure of CDK2 in complex with inhibitor BS-194 2 About this Structure 3 See Also 4 Reference

Crystal structure of CDK2 in complex with inhibitor BS-194

Template:ABSTRACT PUBMED 21080703

About this Structure

3ns9 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2

Reference

• Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, Snyder JP, Liotta DC, Freemont PS, Aboagye EO, Coombes RC, Barrett AG, Ali S. A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration. J Med Chem. 2010 Nov 16. PMID:21080703 doi:10.1021/jm100732t