2qq7

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Image:2qq7.png

Template:STRUCTURE 2qq7

Contents

Crystal structure of drug resistant SRC kinase domain with irreversible inhibitor

Template:ABSTRACT PUBMED 18316192

About this Structure

2qq7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  • Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053

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