2hmi

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Template:STRUCTURE 2hmi

Contents 1 HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX 2 About this Structure 3 See Also 4 Reference

HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX

Template:ABSTRACT PUBMED 9837729

About this Structure

2hmi is a 6 chain structure of Monoclonal Antibody and Reverse transcriptase with sequence from Human immunodeficiency virus 1 and Mus musculus. This structure supersedes the now removed PDB entry 1hmi. The September 2002 RCSB PDB Molecule of the Month feature on Reverse Transcriptase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_9. Full crystallographic information is available from OCA.

See Also

• Monoclonal Antibody
• Reverse transcriptase

Reference

• Ding J, Das K, Hsiou Y, Sarafianos SG, Clark AD Jr, Jacobo-Molina A, Tantillo C, Hughes SH, Arnold E. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. J Mol Biol. 1998 Dec 11;284(4):1095-111. PMID:9837729 doi:10.1006/jmbi.1998.2208
• Menendez-Arias L. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis. Biochemistry. 1998 Nov 24;37(47):16636-44. PMID:9843431 doi:10.1021/bi981830g