2rf2

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2rf2

Contents 1 HIV reverse transcriptase in complex with inhibitor 7e (NNRTI) 2 About this Structure 3 See Also 4 Reference

HIV reverse transcriptase in complex with inhibitor 7e (NNRTI)

Template:ABSTRACT PUBMED 18083561

About this Structure

2rf2 is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

See Also

• Reverse transcriptase

Reference

• Zhao Z, Wolkenberg SE, Sanderson PE, Lu M, Munshi V, Moyer G, Feng M, Carella AV, Ecto LT, Gabryelski LJ, Lai MT, Prasad SG, Yan Y, McGaughey GB, Miller MD, Lindsley CW, Hartman GD, Vacca JP, Williams TM. Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Bioorg Med Chem Lett. 2008 Jan 15;18(2):554-9. Epub 2007 Nov 28. PMID:18083561 doi:10.1016/j.bmcl.2007.11.085