3sl3

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3sl3

Contents 1 Crystal structure of the apo form of the catalytic domain of PDE4D2 2 About this Structure 3 See Also 4 Reference

Crystal structure of the apo form of the catalytic domain of PDE4D2

Template:ABSTRACT PUBMED 22030030

About this Structure

3sl3 is a 4 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Phosphodiesterase

Reference

• Nankervis JL, Feil SC, Hancock NC, Zheng Z, Ng HL, Morton CJ, Holien JK, Ho PW, Frazzetto MM, Jennings IG, Manallack DT, Martin TJ, Thompson PE, Parker MW. Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7089-93. Epub 2011 Oct 5. PMID:22030030 doi:10.1016/j.bmcl.2011.09.109