1o5m
From Proteopedia
Contents |
Structure of FPT bound to the inhibitor SCH66336
Template:ABSTRACT PUBMED 10377218
About this Structure
1o5m is a 2 chain structure of Farnesyltransferase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships. J Med Chem. 1999 Jun 17;42(12):2125-35. PMID:10377218 doi:http://dx.doi.org/10.1021/jm990030g
