3ns7

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Template:STRUCTURE 3ns7

Contents 1 Succinic Acid Amides as P2-P3 Replacements for Inhibitors of Interleukin-1beta Converting Enzyme (ICE or Caspase 1) 2 About this Structure 3 See Also 4 Reference

Succinic Acid Amides as P2-P3 Replacements for Inhibitors of Interleukin-1beta Converting Enzyme (ICE or Caspase 1)

Template:ABSTRACT PUBMED 20656488

About this Structure

3ns7 is a 2 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Caspase

Reference

• Galatsis P, Caprathe B, Gilmore J, Thomas A, Linn K, Sheehan S, Harter W, Kostlan C, Lunney E, Stankovic C, Rubin J, Brady K, Allen H, Talanian R. Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1). Bioorg Med Chem Lett. 2010 Sep 1;20(17):5184-90. Epub 2010 Jul 8. PMID:20656488 doi:10.1016/j.bmcl.2010.07.004