1pfq

From Proteopedia

Revision as of 16:36, 12 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1pfq.gif

1pfq, resolution 1.90Å

Drag the structure with the mouse to rotate

crystal structure of human apo dipeptidyl peptidase IV / CD26

Overview

Dipeptidyl peptidase IV is a multifunctional type II transmembrane serine, protease glycoprotein. The high-resolution crystal structure of the, homodimeric human apo dipeptidyl peptidase IV has been determined at 1.9 A, resolution. In addition, the structure of the binary complex with, 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrol, idine has been solved, revealing the nature of the covalent interaction, with the active-site serine.

About this Structure

1PFQ is a Single protein structure of sequence from Homo sapiens with NAG as ligand. Active as Dipeptidyl-peptidase IV, with EC number 3.4.14.5 Full crystallographic information is available from OCA.

Reference

High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrol idine., Oefner C, D'Arcy A, Mac Sweeney A, Pierau S, Gardiner R, Dale GE, Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1206-12. Epub 2003, Jun 27. PMID:12832764

Page seeded by OCA on Mon Nov 12 18:43:11 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pfq"
Personal tools