RA Mediated T-reg Differentiation

From Proteopedia

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Introduction

T-regulatory cells (T-regs) are a small subset of CD4+ T-cells that exhibit strong down regulation of immune system activity in their local environment. They are distinguished from other CD4+ T-cells by the expression of FOXP3, a gene regulator.

spinqualitylabelsall models RARα-RXRα interaction (PDB entry 1dkf) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Ligand Binding Domain RARα-RXRα Heterodimer RARα-RXRα Ligand Interactions

spinqualitylabelsall models Crystal structure of RXRα-DNA complex PDB entry 1BY4 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image DNA Binding Domain RXRα-DNA Interactions DR-5 Specificity

Biological Significance

References