This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Transketolase
From Proteopedia
Transketolase (TKT) catalyzes two opposite reactions. The synthesis of sedoheptulose-7-P in the pentose phosphate pathway using thiamine diphosphate (TPP) as co-factor; and the conversion of sedoheptulose-7-P and glyceraldehyde-3-P to aldose and ketose in the Calvin cycle.
Contents |
3D Structures of transketolase
Update July 2012
1trk – yTKT – yeast
1ay0 – yTKT (mutant)
2e6k – TKT – Thermus thermophilus
3hyl – BaTKT – Bacillus anthracis
3kom – TKT (mutant) – Francisella tularensis
3l84 – CjTKT – Campylobacter jejuni
3rim – TKT – Mycobacterium tuberculosis
3uk1 – BtTKT – Burkholderia thailandensis
Transketolase binary complexes
3m49 – BaTKT + TPP
3mos, 3ooy – TKT + TPP - human
1tka, 1tkb, 1tkc – yTKT + TPP analog
1gpu - yTKT + TPP derivative
1itz - TKT + TPP – maize
1qgd - EcTKT + TPP – Escherichia coli
1r9j - TKT + TPP – Leishmania mexicana
Transketolase ternary complexes
3m7i, 3m6l – CjTKT + TPP + ribose 5-P
3m34 - CjTKT + TPP + Ca
1ngs - yTKT + TPP + Ca + erythrose-4-P
2r5n – EcTKT + TPP + ribose 5-P
3upt - BtTKT + TPP + ribose 5-P
2r8o - EcTKT + TPP + xylulose 5-P
2r8p - EcTKT + TPP + fructose 6-P
