1qfx

From Proteopedia

Revision as of 22:32, 20 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1qfx.jpg

1qfx, resolution 2.4Å

Drag the structure with the mouse to rotate

PH 2.5 ACID PHOSPHATASE FROM ASPERGILLUS NIGER

Overview

The crystal structure of Aspergillus niger pH 2.5 acid phosphatase (EC, 3.1.3.2) has been determined at 2.4 A resolution. In the crystal, two, dimers form a tetramer in which the active sites are easily accessible to, substrates. The main contacts in the dimer come from the N termini, each, lying on the surface of the neighbouring molecule. The monomer consists of, two domains, with the active site located at their interface. The active, site has a highly conserved catalytic center and a charge distribution, which explains the highly acidic pH optimum and the broad substrate, specificity of the enzyme.

About this Structure

1QFX is a Single protein structure of sequence from Aspergillus niger with NAG, SO4 and GOL as ligands. Active as 3-phytase, with EC number 3.1.3.8 Full crystallographic information is available from OCA.

Reference

Crystal structure of Aspergillus niger pH 2.5 acid phosphatase at 2. 4 A resolution., Kostrewa D, Wyss M, D'Arcy A, van Loon AP, J Mol Biol. 1999 May 21;288(5):965-74. PMID:10329192

Page seeded by OCA on Wed Nov 21 00:39:15 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qfx"
Personal tools