1qoj
From Proteopedia
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CRYSTAL STRUCTURE OF E.COLI UVRB C-TERMINAL DOMAIN, AND A MODEL FOR UVRB-UVRC INTERACTION.
Overview
A crystal structure of the C-terminal domain of Escherichia coli UvrB, (UvrB') has been solved to 3.0 A resolution. The domain adopts a, helix-loop-helix fold which is stabilised by the packing of hydrophobic, side-chains between helices. From the UvrB' fold, a model for a domain of, UvrC (UvrC') that has high sequence homology with UvrB' has been made. In, the crystal, a dimerisation of UvrB domains is seen involving specific, hydrophobic and salt bridge interactions between residues in and close to, the loop region of the domain. It is proposed that a homologous mode of, interaction may occur between UvrB and UvrC. This interaction is likely to, be flexible, potentially spanning > 50 A.
About this Structure
1QOJ is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of Escherichia coli UvrB C-terminal domain, and a model for UvrB-uvrC interaction., Sohi M, Alexandrovich A, Moolenaar G, Visse R, Goosen N, Vernede X, Fontecilla-Camps JC, Champness J, Sanderson MR, FEBS Lett. 2000 Jan 14;465(2-3):161-4. PMID:10631326
Page seeded by OCA on Wed Nov 21 00:50:51 2007
