1i85

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Image:1i85.png

Template:STRUCTURE 1i85

Contents

CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX

Template:ABSTRACT PUBMED 11279501

Disease

Known disease associated with this structure: Celiac disease, susceptibility to OMIM:[123890], Diabetes mellitus, insulin-dependent, susceptibility to OMIM:[123890], Graves disease, susceptibility to OMIM:[123890], Hypothyroidism, autoimmune OMIM:[123890]

About this Structure

1I85 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schwartz JC, Zhang X, Fedorov AA, Nathenson SG, Almo SC. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature. 2001 Mar 29;410(6828):604-8. PMID:11279501 doi:10.1038/35069112

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