Template:STRUCTURE 1h8f

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1h8f, resolution 2.80Å ()

Sites:

Ligands:

Activity:

Non-specific serine/threonine protein kinase, with EC number 2.7.11.1

Domains:

Structural annotation:
Resources:	CATH : 1H8Fa02, 1H8Fa01, 1H8Fb02, 1H8Fb01 InterPro : Ipr011009, Ipr000719, Ipr008271, Ipr002290 Pfam : PF00069 SCOP : d1h8fa_, d1h8fb_ UniProt : P49841

Functional annotation:
Resources:	GeneCard : GSK3B
Cellular component:	cytoplasm nucleus beta-catenin destruction complex
Biological process:	positive regulation of protein export from nucleus peptidyl-serine phosphorylation Wnt receptor signaling pathway through beta-catenin ER overload response Wnt receptor signaling pathway negative regulation of apoptosis protein amino acid phosphorylation intracellular signaling cascade glycogen metabolic process
Molecular function:	nucleotide binding ATP binding transferase activity p53 binding NF-kappaB binding kinase activity protein serine/threonine kinase activity protein kinase activity protein binding glycogen synthase kinase 3 activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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