1rii
From Proteopedia
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Crystal structure of phosphoglycerate mutase from M. Tuberculosis
Overview
The single-crystal X-ray structure of phosphoglycerate mutase from, Mycobacterium tuberculosis has been determined at a resolution of 1.70, angstroms. The C-terminal tail of each of the subunits is flexible and, disordered; however, for one of the four chains (chain A) all but five, residues of the chain could be modeled. Noteworthy features of the, structure include the active site and a proline-rich segment in each, monomer forming a short left-handed polyprolyl helix. These segments lie, on the enzyme surface and could conceivably participate in protein-protein, interactions.
About this Structure
1RII is a Single protein structure of sequence from Mycobacterium tuberculosis with GOL as ligand. Active as Phosphoglycerate mutase, with EC number 5.4.2.1 Full crystallographic information is available from OCA.
Reference
The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase., Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D, Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. Epub 2005, Feb 24. PMID:15735341
Page seeded by OCA on Wed Nov 21 01:37:28 2007
Categories: Mycobacterium tuberculosis | Phosphoglycerate mutase | Single protein | Chan, S. | Eisenberg, D. | Mueller, P. | Pashkova, I. | Perry, J. | Sawaya, M.R. | TBSGC, TB.Structural.Genomics.Consortium. | Wu, Y. | GOL | Phosphoglyerate mutase | Protein structure initiative | Psi | Sh3 domain binding | Structural genomics | Tb structural genomics consortium | Tbsgc
