1rnd

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Image:1rnd.gif

1rnd, resolution 1.5Å

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NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE

Overview

Dinucleotides containing guanine, when soaked into crystals of bovine, pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This, finding has prompted a reexamination of three mononucleotide-RNase, complexes from this laboratory resulting in a re-interpretation of the, complex that involved a guanine mononucleotide.

About this Structure

1RND is a Single protein structure of sequence from Bos taurus with SO4 and DGP as ligands. Active as Pancreatic ribonuclease, with EC number 3.1.27.5 Full crystallographic information is available from OCA.

Reference

Newly observed binding mode in pancreatic ribonuclease., Aguilar CF, Thomas PJ, Mills A, Moss DS, Palmer RA, J Mol Biol. 1992 Mar 5;224(1):265-7. PMID:1548704

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