1n0w

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Image:1n0w.png

Template:STRUCTURE 1n0w

Contents

Crystal structure of a RAD51-BRCA2 BRC repeat complex

Template:ABSTRACT PUBMED 12442171

Disease

Known disease associated with this structure: Breast cancer 2, early onset OMIM:[600185], Fanconi anemia, complementation group D1 OMIM:[600185], Pancreatic cancer OMIM:[600185], Prostate cancer OMIM:[600185], Wilms tumor OMIM:[600185], Breast cancer, male, susceptibility to OMIM:[600185], Glioblastoma OMIM:[600185], Medulloblastoma OMIM:[600185], Pre-B-cell acute lymphoblastic leukemia , OMIM:[600185]

About this Structure

1N0W is a 4 chains structure of sequences from [1] and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, Venkitaraman AR. Insights into DNA recombination from the structure of a RAD51-BRCA2 complex. Nature. 2002 Nov 21;420(6913):287-93. Epub 2002 Nov 10. PMID:12442171 doi:10.1038/nature01230

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