1o5d
From Proteopedia
Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
Template:ABSTRACT PUBMED 15522303
About this Structure
1o5d is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Katz BA, Luong C, Ho JD, Somoza JR, Gjerstad E, Tang J, Williams SR, Verner E, Mackman RL, Young WB, Sprengeler PA, Chan H, Mortara K, Janc JW, McGrath ME. Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J Mol Biol. 2004 Nov 19;344(2):527-47. PMID:15522303 doi:10.1016/j.jmb.2004.09.032
Categories: Coagulation factor VIIa | Homo sapiens | Chan, H. | Gjerstad, E. | Ho, J D. | Janc, J W. | Katz, B A. | Luong, C. | Mackman, R L. | McGrath, M E. | Mortara, K. | Somoza, J R. | Sprengeler, P A. | Tang, J. | Verner, E. | Williams, S R. | Young, W B. | Ala190 upa | Blood clotting | Conserved water displacement hydrogen bond deficit | Factor viia | Hepsin | Hydrolase | S1 site | Selectivity | Thrombin | Trypsin
