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Designations of the protein: Human soluble epoxide hydrolase, Bifunctional epoxide hydrolase 2. Organism: Homo sapiens. Sequence length: 555 residues. Oligomerization state: Homodimer. Gene name: EPHX2. Catalytic domains: 1/ Lipid-phosphate phosphatase EC=3.1.3.76 . 2/ Cytosolic epoxide hydrolase 2 EC=3.3.2.10

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X-ray crystal structure of hsEH: assymetric unit, 1s8o

Ligands:

Gene:

EPHX2 (Homo sapiens)

Activity:

Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10

Related:

1vj5

Structural annotation:
Resources:	InterPro : Ipr011945, Ipr005834, Ipr006402, Ipr003089, Ipr005833, Ipr000639, Ipr000073 Pfam : PF00702, PF00561 SCOP : d1s8oa2, d1s8oa1 UniProt : P34913

Functional annotation:
Cellular component:	peroxisome soluble fraction cytosol cytoplasm
Biological process:	oxygen and reactive oxygen species metabolic process cellular calcium ion homeostasis inflammatory response response to toxin metabolic process positive regulation of vasodilation xenobiotic metabolic process drug metabolic process aromatic compound metabolic process aromatic compound catabolic process regulation of blood pressure
Molecular function:	magnesium ion binding catalytic activity epoxide hydrolase activity metal ion binding hydrolase activity protein homodimerization activity