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PDB ID 1s8o

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X-ray crystal structure of hsEH: assymetric unit, 1s8o
Ligands:
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Human Soluble Epoxide Hydrolase: Biological assembly, 1s8o
Human Soluble Epoxide Hydrolase: Biological assembly, 1s8o

Contents

Overview

X-ray crystal structure of hsEH

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Structure

The Human soluble Epoxide hydrolase is a homodimer. Each subunit has , linked by a proline-rich section. The C-terminal domain is called Cytosolic epoxide hydrolase 2: it catalyzes the trans-addition of water to epoxides in order to product glycols. The is made of five residues. The two tyrosines (Y383 and Y466) plays a role.


Mechanism

Inhibitors

External ressources

References

Proteopedia Page Contributors and Editors

DUTREUX Fabien, BONHOURE Anna

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