4dpf
From Proteopedia
BACE-1 in complex with a HEA-macrocyclic type inhibitor
Template:ABSTRACT PUBMED 22698785
About this Structure
4dpf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sandgren V, Agback T, Johansson PO, Lindberg J, Kvarnstrom I, Samuelsson B, Belda O, Dahlgren A. Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: Design, synthesis and X-ray crystal structures of enzyme inhibitor complexes. Bioorg Med Chem. 2012 Jul 15;20(14):4377-89. Epub 2012 May 24. PMID:22698785 doi:10.1016/j.bmc.2012.05.039
