1q3x

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Template:STRUCTURE 1q3x

Contents

Crystal structure of the catalytic region of human MASP-2

Template:ABSTRACT PUBMED 15364579

Disease

Known disease associated with this structure: MASP2 deficiency OMIM:[605102]

About this Structure

1Q3X is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Harmat V, Gal P, Kardos J, Szilagyi K, Ambrus G, Vegh B, Naray-Szabo G, Zavodszky P. The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions. J Mol Biol. 2004 Oct 1;342(5):1533-46. PMID:15364579 doi:10.1016/j.jmb.2004.07.014

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