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Template:Sandbox ESBS 2012

Template:STRUCTURE 2c1m

Contents 1 NUP50:IMPORTIN-ALPHA COMPLEX 2 About this Structure 3 See Also 3.1 IMPORTIN ALPHA STRUCTURE 4 Reference

NUP50:IMPORTIN-ALPHA COMPLEX

Template:ABSTRACT PUBMED 16222336

About this Structure

2c1m is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Nucleoporin

IMPORTIN ALPHA STRUCTURE

Importin α is a soluble adaptor protein also known as karyopherin α. It has as a function to connect importin β and a protein which have a cNLS (classical Nuclear Localization Signal) in order to import this protein in the nucleus.

Reference

• Matsuura Y, Stewart M. Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling. EMBO J. 2005 Nov 2;24(21):3681-9. Epub 2005 Oct 13. PMID:16222336