Template:STRUCTURE 1s8o

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1s8o, resolution 2.60Å ()

Ligands:

Gene:

EPHX2 (Homo sapiens)

Activity:

Microsomal epoxide hydrolase, with EC number 3.3.2.9

Domains:

Abhydrolase_1, PldB, COG1011

Related:

Structural annotation:
Resources:	InterPro : Ipr011945, Ipr005834, Ipr006402, Ipr003089, Ipr005833, Ipr000639, Ipr000073 Pfam : PF00702, PF00561 SCOP : d1s8oa2, d1s8oa1 UniProt : P34913

Functional annotation:
Resources:	GeneCard : EPHX2
Cellular component:	peroxisome soluble fraction cytosol cytoplasm
Biological process:	oxygen and reactive oxygen species metabolic process cellular calcium ion homeostasis inflammatory response response to toxin metabolic process positive regulation of vasodilation xenobiotic metabolic process drug metabolic process aromatic compound metabolic process aromatic compound catabolic process regulation of blood pressure
Molecular function:	magnesium ion binding catalytic activity epoxide hydrolase activity metal ion binding hydrolase activity protein homodimerization activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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